Moderna Vaccine Provokes Strong Immune Response in Children 6 to 11

Moderna’s coronavirus vaccine elicits a strong immune response in children aged 6 to 11, researchers reported on Wednesday — another signpost in what has become a long and tortuous road to protecting young children against the virus, even as cases again inch upward.

On Monday, Moderna requested authorization from the Food and Drug Administration for the vaccine’s use in this age group. But authorization, if granted, is unlikely to bump up the low immunization rates among young children by much.

The Pfizer-BioNTech vaccine has been available for children aged 5 to 11 since November, but as of Wednesday, just 28.7 percent had received two doses. There is no coronavirus vaccine available at all for children younger than 5, forcing parents to rely on less reliable protective measures.

Last month, Moderna asked the F.D.A. to authorize its vaccine for use in children 6 months to 6 years old. The agency is already reviewing the company’s data on adolescents, and is expected to decide on use of the Moderna vaccine in children of all ages in June.

In February, Pfizer and BioNTech also sought authorization of their vaccine for use in the youngest children, but withdrew the application after data suggested that two doses did not produce adequate protection against the Omicron variant.

The companies are banking on a third dose to shore up immunity in children, and the F.D.A. is expected to review those data in June, as well.

“We really can’t do it this way in the future — we can’t leave children to the very last,” said Dr. Sallie Permar, an expert in pediatric vaccines at Weill Cornell Medicine in New York.

The process has been particularly confusing and unfair for parents of the youngest children, who still do not have access to a vaccine more than two years into the pandemic, she said.

It has been nearly a year since Moderna requested F.D.A. authorization for use of its vaccine in adolescents 12 to 17 years. While the agency gave the go-ahead to Pfizer-BioNTech’s vaccine for use in that age group in just three weeks, the agency’s review of Moderna’s vaccine had stalled.

The delay in authorization has been longest in the United States. Europe’s drug regulators

Related Articles

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button